Pronefra® – Kidney Support Supplement for Cats & Dogs

Support your cat or dog’s kidney health with Pronefra® Oral Suspension, a highly palatable liquid renal support supplement designed for adult cats and dogs requiring nutritional support for kidney function and healthy blood phosphorus levels.

Pronefra® combines Calcium Carbonate, Magnesium Carbonate, Chitosan and Marine Oligopeptides (Fish Protein Hydrolysate) to provide multi-action nutritional support.

The formula works within the digestive tract to help bind dietary phosphate and uraemic waste products, while marine oligopeptides provide additional support for maintaining balanced blood pressure.

Its liquid format makes Pronefra® particularly convenient for cats and dogs that dislike tablets or capsules. It can be mixed directly with food or administered into the mouth using the included dosing syringe.

Ideal for adult cats and dogs requiring additional nutritional support as part of a comprehensive kidney-care programme, particularly when maintaining appropriate phosphate levels is an important consideration.

Why You’ll Love It

Supports Healthy Kidney Function

Kidneys play an essential role in filtering waste products and maintaining the body’s mineral and fluid balance.

When kidney function becomes compromised, certain substances such as phosphate and uraemic waste products can accumulate.

Pronefra® provides nutritional support through several complementary mechanisms, helping reduce the digestive absorption of substances that may otherwise place additional demands on compromised kidney function.

Helps Control Dietary Phosphate Absorption

Maintaining appropriate phosphorus levels is an important part of nutritional management for pets with reduced kidney function.

Calcium Carbonate and Magnesium Carbonate act as phosphate-binding ingredients within the digestive tract.

They bind dietary phosphate and reduce its availability for absorption, helping support healthy blood phosphorus levels.

This makes Pronefra® particularly useful alongside an appropriate veterinary renal diet where additional phosphate management may be required.

Supports the Management of Uraemic Waste Products

Pronefra® contains Chitosan, a functional biopolymer that works within the digestive tract.

Chitosan can bind certain uraemic waste products, including compounds associated with protein breakdown, helping reduce their absorption and supporting the body’s overall waste-management processes.

This provides an additional layer of nutritional support for pets with compromised renal function.

Helps Maintain Balanced Blood Pressure

Healthy blood pressure is an important part of maintaining kidney wellbeing.

Pronefra® contains Marine Oligopeptides, also known as fish protein hydrolysate.

These naturally derived peptides provide nutritional support for maintaining balanced blood pressure, which is particularly relevant when supporting pets with compromised kidney function.

Multi-Action Renal Support in One Formula

Pronefra® brings together several functional ingredients to provide comprehensive nutritional support:

• Calcium Carbonate – binds dietary phosphate
• Magnesium Carbonate – contributes additional phosphate-binding support
• Chitosan – binds certain uraemic waste products within the intestine
• Marine Oligopeptides – support balanced blood pressure

This combination provides a broader approach to nutritional kidney support than relying on a single functional ingredient.

Easy Liquid Administration

Cats can be notoriously difficult to medicate, particularly when tablets or capsules are involved.

Pronefra® is supplied as a palatable liquid suspension that can be incorporated directly into food or administered orally using the supplied dosing syringe.

This makes daily administration simple and flexible.

It is particularly useful for pets that:

• Refuse tablets
• Dislike capsules
• Are difficult to medicate
• Prefer liquid supplements
• Need daily nutritional support
• Are already receiving a veterinary renal diet

Highly Palatable and Easy to Accept

Pronefra® has been developed as a tasty liquid formulation to make regular administration easier for both pets and their owners.

The liquid can be mixed with food, helping avoid the need to force tablets or capsules.

For pets that accept direct oral administration, the included syringe provides another convenient option.

Functional Ingredients with Real Purpose

Calcium Carbonate – Phosphate Binding Support

Calcium Carbonate is an inorganic mineral salt with phosphate-binding properties.

When administered with food, it can bind dietary phosphate within the intestine, reducing its availability for absorption.

This helps support nutritional phosphorus management in cats and dogs requiring kidney support.

Magnesium Carbonate – Additional Phosphate Binding

Magnesium Carbonate works alongside Calcium Carbonate as an additional phosphate-binding ingredient.

Together, these mineral salts help reduce the amount of dietary phosphate available for intestinal absorption.

This combination is particularly relevant for animals where maintaining healthy blood phosphorus levels is an important part of renal nutritional management.

Chitosan – Uraemic Waste Binding Support

Chitosan is a functional biopolymer included to help bind certain uraemic waste products within the gastrointestinal tract.

By binding these compounds in the intestine, Chitosan can help reduce their availability for absorption.

This provides additional nutritional support for pets whose kidneys have reduced ability to eliminate metabolic waste.

Marine Oligopeptides – Blood Pressure Support

Marine Oligopeptides, also known as Fish Protein Hydrolysate, are naturally derived peptides obtained from hydrolysed fish protein.

These peptides provide nutritional support for maintaining balanced blood pressure.

Balanced blood pressure is particularly important when supporting overall kidney health.

How It Works

Pronefra® provides renal nutritional support through several complementary actions.

When administered around mealtimes, Calcium Carbonate and Magnesium Carbonate bind dietary phosphate in the digestive tract, helping reduce the amount available for absorption.

At the same time, Chitosan binds certain uraemic waste products, helping reduce their absorption from the intestine.

Marine Oligopeptides provide additional nutritional support for maintaining balanced blood pressure.

Together, these actions help support healthy kidney function and contribute to a comprehensive nutritional approach for adult cats and dogs requiring renal support.

Pronefra® is not intended to replace veterinary treatment or a prescribed renal diet. It should be used as part of an appropriate kidney-care programme.

Benefits at a Glance

• Supports healthy kidney function
• Helps manage dietary phosphate absorption
• Supports healthy blood phosphorus levels
• Helps bind certain uraemic waste products
• Supports balanced blood pressure
• Suitable for adult cats and dogs
• Easy-to-administer liquid format
• Can be mixed with food
• Can be administered directly by oral syringe
• Includes dosing syringe
• Particularly convenient for pets that dislike tablets or capsules

Ingredients

Composition:

• Refined Vegetable Oil (Olive and Coprah)
• Meat and Animal Derivatives (Poultry)
• Crude Lecithin
• Calcium Carbonate – 3.6%
• Fish Protein Hydrolysed – 1.9%
• Glycerol Monooleate
• Chitosan – 1%
• Magnesium Carbonate – 1%

Analytical Constituents

• Crude Oils & Fats: 79.9%
• Crude Protein: 7.6%
• Crude Ash: 4.7%
• Crude Fibre: 0.33%

How to Use

Pronefra® Oral Suspension should be administered at or around mealtimes.

It can either be:

• Mixed directly into your pet’s food
• Administered directly into the mouth using the included dosing syringe

Recommended Dosage

Cats:
1 ml per 4 kg body weight, twice daily.

Dogs:
1 ml per 5 kg body weight, twice daily.

Do not exceed the recommended daily amount.

For best results, divide the recommended daily dosage between the morning and evening meals.

How to Administer Pronefra®

1. Shake the bottle well before each use.
2. Unscrew the white cap to open the bottle.
3. Screw the blue dosing cap onto the bottle.
4. Keep the bottle upright and open the blue cap.
5. Firmly insert the tip of the supplied dosing syringe.
6. Turn the bottle upside down.
7. Gently pull the syringe plunger until the required amount is reached.
8. Use the markings on the syringe to measure the correct dose.
9. Turn the bottle upright again.
10. Gently twist the syringe to remove it from the blue cap.
11. Close the blue cap securely.
12. Carefully empty the syringe into your pet’s food and mix thoroughly.
13. Alternatively, administer directly into your pet’s mouth, ensuring your pet swallows the complete dose.
14. Thoroughly clean the syringe after every use.

Important Administration Advice

Always ensure your pet has free access to fresh drinking water while receiving Pronefra®.

If mixing with food, make sure your pet consumes the complete portion containing the supplement.

If your pet is receiving a prescribed veterinary renal diet, medication or other supplements, consult your veterinarian before introducing Pronefra®.

Suitable for Adult Cats & Dogs

Pronefra® is formulated for adult cats and dogs requiring nutritional support for kidney function and phosphorus management.

It may be particularly appropriate for pets requiring additional support as part of a veterinary-managed renal care plan.

Because kidney disease can vary significantly between individual animals, supplementation should always take into account the pet’s overall health, diet, blood results and existing medication.

When Might Pronefra® Be Particularly Useful?

Pronefra® may provide useful nutritional support for adult pets when:

• Kidney function requires additional nutritional support
• Dietary phosphate management is important
• Blood phosphorus levels need to be carefully managed
• A pet requires additional support alongside a veterinary renal diet
• Tablet administration is difficult
• A liquid supplement is easier to administer
• Additional support for uraemic waste management is desired
• Maintaining balanced blood pressure is part of the overall kidney-care strategy

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Research Behind Pronefra®

Pronefra® is formulated using ingredients that have been investigated in veterinary and nutritional research, particularly in relation to phosphate management, kidney support and blood pressure.

• Chitosan & Calcium: Studied for their effects on calcium and phosphorus metabolism in cats. Wagner et al. (2004)
• Marine Oligopeptides: Research has investigated food-derived peptides and their potential role in supporting balanced blood pressure. Pripp (2008)
• Pronefra® Formula: A study investigated the effects of Pronefra® on blood parameters and mineral balance in adult cats. Bernachon et al. (2014)
• Magnesium Binders: Research has examined the use of magnesium-containing phosphate binders in chronic kidney disease. Spiegel (2007)

These studies provide scientific background for the ingredients and nutritional principles used in Pronefra®. They do not mean that the product cures or reverses kidney disease.

Frequently Asked Questions

What is Pronefra® used for?

Pronefra® is a liquid nutritional supplement designed to support healthy kidney function in adult cats and dogs.

It helps support phosphorus management through phosphate-binding ingredients and provides additional nutritional support for uraemic waste management and balanced blood pressure.

Does Pronefra® reduce phosphate?

Pronefra® contains Calcium Carbonate and Magnesium Carbonate, which bind dietary phosphate in the digestive tract and reduce its availability for absorption.

This can help support healthy blood phosphorus levels as part of an appropriate renal nutritional programme.

Can Pronefra® be given with regular food?

Yes. Pronefra® can be mixed with your pet’s regular food and given at or around mealtimes.

However, if your veterinarian has prescribed a specific renal diet, follow their dietary recommendations and discuss supplementation with them.

Can Pronefra® be given directly into the mouth?

Yes. Pronefra® can be administered directly into the mouth using the included dosing syringe.

Make sure your pet swallows the complete dose.

Is Pronefra® suitable for cats?

Yes. Pronefra® is suitable for adult cats.

The recommended cat dosage is 1 ml per 4 kg body weight, twice daily.

Is Pronefra® suitable for dogs?

Yes. Pronefra® is suitable for adult dogs.

The recommended dog dosage is 1 ml per 5 kg body weight, twice daily.

Can Pronefra® be used alongside a renal diet?

Pronefra® can be used as nutritional support alongside a veterinary renal diet where appropriate.

Because each pet’s nutritional requirements are different, consult your veterinarian before introducing supplementation.

Does Pronefra® replace veterinary treatment?

No.

Pronefra® is a nutritional support supplement and should not replace veterinary treatment, prescribed medication, blood testing or a veterinary renal diet.

Pet parent review

“The liquid format made kidney support much easier for my cat. I can mix it into his food instead of trying to give him another tablet, and the included syringe makes measuring the dose straightforward.” Margaret H.

Veterinary Advice

Kidney disease is a complex condition that requires individualised management.

If your cat or dog has been diagnosed with kidney disease, we strongly recommend regular veterinary check-ups and appropriate blood and urine monitoring.

Your veterinarian can assess kidney function, phosphorus levels, blood pressure, hydration and nutritional status and determine whether Pronefra® is appropriate for your pet.

Always consult your veterinarian before giving Pronefra®, particularly if your pet is taking medication, following a prescribed renal diet, has advanced kidney disease, or has other underlying health conditions.

Do not change, stop or replace prescribed veterinary treatment without professional advice.